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Les mecanismes de resistance des cellules tumorales sont le plus souvent multifactoriels. Le mieux etudie est le phenotype << MDR >>, pour multi-drug resistance, qui interesse des cytostatiques majeurs (anthracyclines, vinca-alcaloides, epipodophyllotoxines). Il est du a la presence de proteines de transport (proteines ABC) capables d'effluer ces cytostatiques, tous d'origine naturelle...
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