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Bone marrow mononuclear cells (BMMNCs) can counteract oxidative stress and inhibit the inflammatory response in focal ischemic stroke models. However, the effect of BMMNC transplantation on carotid atherosclerosis needs to be determined. The carotid atherosclerotic plaque model was established in New Zealand White rabbits by balloon injury and 8 weeks of high-fat diet. Rabbits were randomized to receive...
ObjectivesReducing the expression of endothelial cell adhesion molecules is conducive to the decrease of inflammation‐induced vascular complications. In this study, we observed pitavastatin on expression of vascular cell adhesion molecule‐1 (VCAM‐1) and its influence on VCAM‐1's target gene miR‐126 in endothelial cells. The purpose of this study is to explore the mechanism of pitavastatin in prevention...
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