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Background and Purpose
We investigated the effects of aging, white matter hyperintensities (WMH), and cognitive impairment on brain iron levels and cerebral oxygen metabolism, known to be altered in Alzheimer's disease (AD), using quantitative susceptibility mapping and MR‐based cerebral oxygen extraction fraction (OEF).
Methods
In 100 individuals over the age of 50 (68/32 cognitively impaired/intact),...
ABSTRACT
OBJECTIVEThe results of prematurely terminated stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) due to excessively high rate of stroke and death in patients randomized to intracranial stent placement is expected to affect the practice of endovascular therapy for intracranial atherosclerotic disease. The purpose of this report...
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