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Flexible Optoelectronics
In article number 2205038, Huae Xu, Hongyi Liu, Jing Ji, Yun Chen, and co‐workers present an injectable, reactive oxygen species‐responsive therapeutic hydrogel (ADU‐AAV‐PD1@Gel), capable of sustained local release of soluble PD‐1 (sPD‐1) and STING agonist ADU‐S100. The ADU‐AAV‐PD1@Gel combined with radiotherapy generates a robust antitumor immune response and induces long‐term...
Tumor recurrence remains the major cause of management failure after surgical resection of glioblastoma (GBM). Immunotherapy has the potential to effectively eradicate tumors and trigger immune memory to prevent tumor recurrence but not improve the outcomes of GBM patients. Here, an injectable, reactive oxygen species‐degradable therapeutic hydrogel (ADU‐AAV‐PD1@Gel), capable of sustained local release...
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