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The insecticidal activity of a natural compound combretastatin A-4 (CA-4) was assessed in in vivo assays against Spodoptera litura. CA-4, mixed into an artificial diet, caused various effects, depending on the concentration used. Compared with controls, food intake was lower, larval growth was reduced and larval development prolonged. Pupae weight was reduced, and adult morphology was also affected...
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