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p73, a structural and functional homolog of p53, plays an important role in tumor carcinogenesis. Previous studies have suggested that the association between the p73 G4C14‐to‐A4T14 polymorphism and the risk of lung cancer, but the results have not been entirely consistent. We examined whether the p73 G4C14‐to‐A4T14 polymorphism was related to the risk of developing lung cancer in a Chinese population...
The synthetic selenium compound methylseleninic acid (MSA) is a direct precursor of active methylselenol and appears to be the best candidate for studies on the mechanisms of selenium cancer prevention and therapy in vitro. Reduced glutathione (GSH) is critical to MSA metabolism, in addition to being a protective antioxidant which scavenges reactive oxygen species (ROS) and maintains the stability...
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