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Both CIEF and MALDI‐MS are frequently used in protein analysis, but hyphenation of the two has not been investigated proportionally. One of the major reasons is that the additives (such as carrier ampholytes and detergent) in CIEF severely suppress the MALDI‐MS signal, which hampers the hyphenation of the two. In this paper, we develop a simple means to alleviate the above signal‐suppressing effect...
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