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Inhibition of SARS‐CoV‐2 Variants
In the article number 2206154, Ievgen S. Donskyi and co‐workers describe effective SARS‐CoV‐2 inhibitor. Low molecular weight polyglycerol sulfate works in tandem with a single hydrophobic fullerene to prevent the infection in vitro. Investigated through plaque reduction assays, microscale thermophoresis (MST) binding studies, and molecular dynamics (MD) simulations,...
As virus outbreaks continue to pose a challenge, a nonspecific viral inhibitor can provide significant benefits, especially against respiratory viruses. Polyglycerol sulfates recently emerge as promising agents that mediate interactions between cells and viruses through electrostatics, leading to virus inhibition. Similarly, hydrophobic C60 fullerene can prevent virus infection via interactions with...
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