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As mediators of pyroptosis, gasdermins (GSDMs) are closely associated with systemic cytotoxicity or so‐called side effects and are also involved in the inflammatory response during chemotherapy. Using in situ proximity ligation assay followed by sequencing (isPLA‐seq), which we recently developed, we screened a single‐domain antibody (sdAb) library and identified several sdAbs against Gasdermin E...