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Background and Aim
The incidence and consequences of flares during first‐line nucleos(t)ide analogue therapy are largely unknown. We aimed to investigate the incidence and outcome of alanine aminotransferase (ALT) flares during long‐term entecavir (ETV) in chronic hepatitis B (CHB).
Methods
CHB patients treated with ETV monotherapy from 11 European centers were studied. Flare was defined as >...
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