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Parallel and sequential manipulation of trapping, labeling and content extraction of single cell was realized using a 2-D simple flow channels. The proposed system consists of main channels, cell trapping pockets, drain channels and single cell content collection channels. We fabricated prototypes having 16 cell trapping pockets and 512 cell trapping pockets. Sequential all single cell handling for...
A novel flow type electrochemical immuno sensing system using 3-D comb electrodes, which enables high-speed enzyme immunoassay on a single microchip, has been developed. A trap-and-release system of magnetic beads and a sheath flow sorting system are integrated on the chip. The integrated system realizes repeatable sample preparation and sensing. Using this system, AFP detection in the range from...
A simple DNA diagnosis method using microfluidics has been developed which requires simple and straightforward procedures such as injection of sample and probe DNA solutions. This method takes advantage of the highly accurate control of fluids in microchannels, and is superior to DNA microarray diagnosis methods due to its simplicity, highly quantitative determination, and high-sensitivity. The method...
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