Search results for: Iris Sawazaki‐Calone

Items from 1 to 7 out of 7 results

article

Trophoblast cell surface antigen 2 expression predicts outcome in oral squamous cell carcinomas

Mauricio Rocha Dourado, Renato Assis Machado, Lívia Máris Ribeiro Paranaíba, Wilfredo Alejandro González‐Arriagada, more

Oral Diseases > 28 > 4 > 1085 - 1093

Background Trophoblast cell surface antigen 2 (TROP2) has unclear clinical role in oral squamous cell carcinomas (OSCC). Here, we investigated the association of TROP2 immunoexpression with clinicopathological parameters and survival of OSCC patients. Subjects and Methods Cancer‐specific survival (CSS) and disease‐free survival (DFS) were assessed in a cohort composed of 266 OSCC. An independent...

article

Prognostication for oral carcinomas based on two histological scoring systems (BD and iBD models)

Catherine Bueno Domingueti, Karen Yumie Mendonça Miwa, Mauricio Rocha Dourado, Íris Sawazaki‐Calone, more

Oral Diseases > 27 > 4 > 894 - 899

article

Prognostication for oral squamous cell carcinoma patients based on the tumour–stroma ratio and tumour budding

Maurício R Dourado, Karen Y M Miwa, Guilherme B Hamada, Lívia M R Paranaíba, more

Histopathology > 76 > 6 > 906 - 918

Aims Previous studies have demonstrated that the tumour–stroma ratio (TSR) and tumour budding are of prognostic value for oral squamous cell carcinomas (OSCCs). The aim of this study was to evaluate the prognostic significance of those histological parameters, individually and in combination, for OSCC. Methods and results The TSR and tumour budding (the presence of five or more buds at the invasive...

article

Machine learning application for prediction of locoregional recurrences in early oral tongue cancer: a Web-based prognostic tool

Rasheed Omobolaji Alabi, Mohammed Elmusrati, Iris Sawazaki-Calone, Luiz Paulo Kowalski, more

Virchows Archiv > 2019 > 475 > 4 > 489-497

Estimation of risk of recurrence in early-stage oral tongue squamous cell carcinoma (OTSCC) remains a challenge in the field of head and neck oncology. We examined the use of artificial neural networks (ANNs) to predict recurrences in early-stage OTSCC. A Web-based tool available for public use was also developed. A feedforward neural network was trained for prediction of locoregional recurrences...

article

Clinicopathologic significance of ROCK2 expression in oral squamous cell carcinomas

Mauricio R. Dourado, Carine E. Oliveira, Iris Sawazaki‐Calone, Elias Sundquist, more

Journal of Oral Pathology & Medicine > 47 > 2 > 121 - 127

Background Rho‐associated coiled‐coil kinase 2 (ROCK2) is an oncoprotein that controls cytoskeleton organization and acts as prognostic marker in different types of solid tumors. ROCK2 overexpression is also observed in cancer‐associated fibroblasts (CAF), which suggests its relevance within the tumor microenvironment. This study aimed to access the prognostic value of ROCK2 in oral squamous cell...

article

Different patterns of expression of cell cycle control and local invasion‐related proteins in oral squamous cell carcinoma affecting young patients

Marisol Miranda Galvis, Alan Roger Santos‐Silva, Juscelino Freitas Jardim, Felipe Paiva Fonseca, more

Journal of Oral Pathology & Medicine > 47 > 1 > 32 - 39

Objectives Oral squamous cell carcinoma (OSCC) predominantly affects males in the fifth decade of life; nevertheless, an increased incidence in young patients has been reported worldwide, and the clinical and behavioral characteristics of tumors in this group are controversial, and the literature shows divergent results. Purpose To investigate the clinicopathological features and prognostic significance...

article

Secretome profiling of oral squamous cell carcinoma-associated fibroblasts reveals organization and disassembly of extracellular matrix and collagen metabolic process signatures

Elizabete Bagordakis, Iris Sawazaki-Calone, Carolina Carneiro Soares Macedo, Carolina M. Carnielli, more

Tumor Biology > 2016 > 37 > 7 > 9045-9057

An important role has been attributed to cancer-associated fibroblasts (CAFs) in the tumorigenesis of oral squamous cell carcinoma (OSCC), the most common tumor of the oral cavity. Previous studies demonstrated that CAF-secreted molecules promote the proliferation and invasion of OSCC cells, inducing a more aggressive phenotype. In this study, we searched for differences in the secretome of CAFs and...

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Search results for: Iris Sawazaki‐Calone

Trophoblast cell surface antigen 2 expression predicts outcome in oral squamous cell carcinomas

Prognostication for oral carcinomas based on two histological scoring systems (BD and iBD models)

Prognostication for oral squamous cell carcinoma patients based on the tumour–stroma ratio and tumour budding

Machine learning application for prediction of locoregional recurrences in early oral tongue cancer: a Web-based prognostic tool

Clinicopathologic significance of ROCK2 expression in oral squamous cell carcinomas

Different patterns of expression of cell cycle control and local invasion‐related proteins in oral squamous cell carcinoma affecting young patients

Secretome profiling of oral squamous cell carcinoma-associated fibroblasts reveals organization and disassembly of extracellular matrix and collagen metabolic process signatures

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