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The impact of SARS‐CoV‐2 infection shortly after vaccination on vaccine‐induced immunity is unknown, which is also one of the concerns for some vaccinees during the pandemic. Here, based on a cohort of individuals who encountered BA.5 infection within 8 days after receiving the fourth dose of a bivalent mRNA vaccine, preceded by three doses of inactivated vaccines, we show that booster mRNA vaccination...
Background
Toll‐like receptor 4 (TLR4)‐mediated inflammatory responses are associated with diabetes and periodontitis, which are dysregulated by O‐GlcNAcylation.
Objective
This study aimed to investigate the effects of O‐GlcNAc transferase (OGT)‐mediated TLR4 O‐GlcNAcylation on the osteogenesis of periodontal ligament stem cells (PDLCs).
Methods
PDLCs were treated with high glucose (HG) to establish...