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Serum-free mouse embryo (SFME) cells, the astrocyte progenitor cells in the central nervous system, generated a self-sustaining feedback loop for glial fibrillary acidic protein (GFAP) expression after a period of cell passages. The period required was about 150days (30 passages). SFME and high-GFAP-expressing SFME (G-SFME) cells were exposed to 10ng/ml leukemia inhibitory factor (LIF) and 10ng/ml...
The effects of bisphenol A (BPA) on the differentiation of serum-free mouse embryo (SFME) cells, the astrocyte progenitor cells in the central nervous system, were examined. SFME cells were exposed to 10ng/ml leukemia inhibitory factor (LIF) and 10ng/ml bone morphogenetic protein 2 (BMP2) to increase glial fibrillary acidic protein (GFAP) expression and induce cell differentiation. Various concentrations...
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