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BackgroundThe human fetus is able to mount a systemic inflammatory response when exposed to microorganisms. This stereotypic response has been termed the ‘fetal inflammatory response syndrome’ (FIRS), defined as an elevation of fetal plasma interleukin‐6 (IL‐6). FIRS is frequently observed in patients whose preterm deliveries are associated with intra‐amniotic infection, acute inflammatory lesions...
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