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Background and ObjectivesEpithelial to mesenchymal transition (EMT) is considered to play an important role in cancer invasion. Tumor budding is a prognostic factor in esophageal squamous cell carcinoma (ESCC). The aim of this study was to explore the correlation between EMT and tumor budding.
MethodsSurgical specimens from 78 cases of ESCC resected without preoperative treatment between 2001 and...
BackgroundEstablishing a new prognostic factor for early‐stage cancer may seem difficult due to the small number of disease‐specific deaths. Tumor budding has been recognized as a useful microscopic finding reflecting biological activity of the tumor.
MethodsTumor budding stand for isolated single cancer cells and cell clusters scattered beyond the tumor margin at the invasive front. It was searched...
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