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Lead poisoning in adults can affect the peripheral and central nervous systems, the kidneys, and blood pressure. Thus, the development of environment-friendly and simple methods for Pb2+ detection is of great importance. Herein, a label-free colorimetric method has been developed for the detection of Pb2+ based on the conformational switch from single-stranded DNA to G-quadruplex. The electrostatic...
Single-stranded telomeric DNA tends to fold into G-quadruplexes made of a stack of G-quartets. Ligands that target G-quadruplex DNA have received considerable attention because of their potential anticancer activity. In this paper, we designed a fluorescence resonance energy transfer system to identify drugs that form G-quadruplexes with human telomeric DNA in a homogeneous medium using gold nanorods...
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