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Aims
To evaluate whether activating α7 nicotinic acetylcholine receptor (α7nAChR) could inhibit the NOD‐like receptor family, pyrin domain containing 3 (NLRP3) inflammasome through regulation of β‐arrestin‐1 in monocyte/macrophage system, thus contributing to the control of neuroinflammation.
Methods
The protein levels of NLRP3, caspase‐1 (Casp‐1) p20 and proCasp‐1, interleukin‐1β (IL‐1β) p17 and...
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