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Clarithromycin (CLA) is an important drug used to treat various bacterial infections, while its effective bioavailability is limited by the poor water-solubility of the CLA molecule. Subcritical water (SBCW) processes have been demonstrated to be a new promising alternative for the preparation of drug nanoparticles with enhanced dissolution rate. In this work, we reported ultrafine CLA nanoparticles...
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