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The anti‐leishmanial effect of the ‘carbohydrate‐fraction’, isolated from an edible mushroom Astraeus hygrometricus, was evaluated against Leishmania donovani infection both in vitro and in vivo. Ahf‐Car induced the expression of inducible nitric oxide synthase 2 (iNOS2) and pro‐inflammatory cytokines like TNF‐α and IL‐12, with subsequent downregulation of the anti‐inflammatory cytokines as TGF‐β and...
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