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Collagenases are widely used for tissue digestion in experiments due to their potent hydrolysis of connective tissue. CD27, also known as tumor necrosis factor receptor superfamily 7 (TNFRSF7), is limited to be expressed on the cells of the lymphoid lineage. In our preliminary research, we found that CD27 on NK cells was almost disappeared with the digestion of type I collagenase for 90min. This phenomenon...
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