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Background In our previous study, we revealed that MEG3 was a tumor suppressor gene in retinoblastoma and inhibited proliferation of retinoblastoma cells by regulating the activity of the Wnt/β-catenin pathway. Here, we further explored the mechanism of MEG3 inactivation in retinoblastoma. Methods MSP and qRT-PCR were performed to detect the methylation status of MEG3 promoter and levels of MEG3...
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