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Disulfiram (DSF), used since the 1950s in the treatment of alcoholism, is reductively activated to diethyldithiocarbamate and both compounds are thiol‐reactive and readily complex copper. More recently DSF and copper‐DSF (Cu‐DSF) have been found to exhibit potent anticancer activity. We have previously shown that the anti‐diabetic drug metformin is anti‐proliferative and induces an intracellular reducing...
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