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The combined influence of doxorubicin (DOX) and liposomal antisense oligonucleotides (ASOs) targeted to hypoxia-inducible factor 1 α (HIF1A) subunit on the apoptosis signaling pathways and cellular pump and nonpump resistance were investigated. Drug-sensitive A2780 and multidrug-resistant A2780/AD human ovarian carcinoma cells were used. Cells were incubated within 48h in normoxic (21% O 2 ...
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