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Adolescent idiopathic scoliosis (AIS) is a serious health problem affecting 3% of live births all over the world. Many loci associated with AIS have been identified by previous genome wide association studies, but their biological implication remains mostly unclear. In this study, we evaluated the AIS‐associated variants in the 7p22.3 locus by combining in silico, in vitro, and in vivo analyses. rs78148157...
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