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Platycodin D2 (PD2), a saponin isolated from the root of Platycodon grandiflorum, was evaluated for its haemolytic activity and adjuvant potential on the cellular and humoral immune responses to ovalbumin (OVA) in ICR mice. The HD 50 values of PD2 and Quil A were 18.57±1.37 and 5.76±0.23 μg/ml against 0.5% rabbit red blood cell, respectively, implicating the less haemolytic activity for PD2...
The haemolytic activities and adjuvant potentials of Platycodon grandiflorum saponin (PGS) and its fractions on the cellular and humoral immune responses of ICR mice against ovalbumin (OVA) were evaluated. PGS was subjected to silica gel column chromatography to afford four fractions, and two fractions PGSC and PGSD selected for testing for activities because of containing dominant saponin peaks....
Platycodin D (PD), platycodin D3 (PD3), and platycoside E (PE) were the platycodigenin-type saponins isolated from the root of Platycodon grandiflorum. All shared a platycodigenin skeleton and the same sugar side chains attached to C-28 of the aglycone, only differ from one another by the number of glycosyl units in sugar moieties attached to C-3. To assess the potential contribution of the glycidic...
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