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Cystathionine-γ-lyase (CSE) is a major endogenous enzyme producing H2S which, as a third gasotransmitter, plays important roles in many physiological and pathological processes. The mechanism of regulating CSE gene expression is unclear and the roles of CSE/H2S in tumor also have not got a profound understanding, especially in colon cancer. Our study demonstrated that CSE gene expression was regulated...
Hydrogen sulfide (H 2 S) has been found to play an important role as a novel gasotransmitter involved in many biological processes. The regulatory role of endogenous H 2 S-producing enzyme on cancer cell survival is complex and unclear. According to the data that cystathionine γ-lyase (CSE) gene, catalyzed H 2 S production in trans-sulfuration pathway, was upregulated in Akt...
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