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Among the family of regulatory B cells, the subset able to produce interleukin‐10 (IL‐10) is the most studied, yet its biology is still a matter of investigation. The DNA methylation profiling of the il‐10 gene locus revealed a novel epigenetic signature characterizing murine B cells ready to respond through IL‐10 synthesis: a demethylated region located 4.5 kb from the transcription starting site...
An increasing body of literature supports a role for neutrophils as players in the orchestration of adaptive immunity. During acute and chronic inflammatory conditions, neutrophils rapidly migrate not only to sites of inflammation, but also to draining lymph nodes and spleen, where they engage bidirectional interactions with B‐ and T‐lymphocyte subsets. Accordingly, a relevant role of neutrophils...
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