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Purpose Rheumatoid arthritis (RA) involves migration of macrophages into inflamed areas. (R)-[11C]PK11195 binds to peripheral benzodiazepine receptors, expressed on macrophages, and may be used to quantify inflammation using positron emission tomography (PET). This study evaluated methods for the quantification of (R)-[11C]PK11195 binding in the knee joints of RA patients. Methods Data from six...
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