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Techniques that can manipulate micro or macro biomaterials like cells and organisms have been of interest for a wide range of applications from biochemistry to clinical diagnostics and many clever techniques have been developed. However, methods with the ability to directly manipulate nanoscale biomaterials (e.g. proteins or DNAs) are still challenging due to physical limitations like Brownian motions...
Introduction Developing micro/nano scale devices for biosensing applications have triggered a lot interests in recent years. Miniaturizing the transducer size often increases the limit of detections (LOD) of the biosensor which is largely benefited by its high surface to volume ratio. However, fundamental limitations for further improvement of the LOD of micro/nano scale biosensors are the mass transport...
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