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Thraustochytrium is a unicellular marine protist for the commercial production of very long‐chain polyunsaturated fatty acids (VLCPUFAs). Biosynthesis of these VLCPUFAs in the protist is catalysed by a PUFA synthase comprising three subunits, each with multiple catalytic domains. Among these domains, two tandem FabA‐like dehydratase domains (DH1 and DH2) in subunit‐C together are responsible for introducing...
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