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Bergenin is a C‐glucoside of 4‐O‐methyl gallic acid with a variety of biological activities, such as antioxidant and anti‐inflammatory. Herein, we investigated the involvement of bergenin in the protective effect against H2O2‐induced oxidative stress and apoptosis in human nucleus pulposus cells (HNPCs) and the underlying mechanisms. HNPCs were cotreated with various concentrations of bergenin and...
Cellular redox status plays a key role in mediating various physiological and developmental processes often through modulating activities of redox‐sensitive proteins. Various stresses trigger over‐production of reactive oxygen/nitrogen species which lead to oxidative modifications of redox‐sensitive proteins. Identification and characterization of redox‐sensitive proteins are important steps toward...
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