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Objective
Nonadherence to antiseizure drugs is a significant problem in pediatric epilepsy and is linked to increased morbidity and mortality, clinically unnecessary medication changes, and increased health care costs. Family interventions can improve adherence. However, it is challenging to determine which families will struggle with nonadherence and require intervention. This study aims to identify...
Objective
This study was undertaken to examine the efficacy of a family‐tailored education and problem‐solving behavioral intervention, Supporting Treatment Adherence Regimens (STAR), in young children (2–12 years old) with new onset epilepsy compared to an attention control (i.e., education only [EO]) intervention. Participants randomized to the STAR intervention were hypothesized to demonstrate...
Objective
To examine baseline psychological functioning and antiepileptic drug (AED) behavioral side effects in new onset epilepsy and determine, by age, whether baseline psychological functioning predicts AED behavioral side effects 1 month following AED initiation.
Methods
A retrospective chart review was conducted between July 2011 and December 2014 that included youths with new onset epilepsy...
Objective
To validate a brief and reliable epilepsy‐specific, health‐related quality of life (HRQOL) measure in children with various seizure types, treatments, and demographic characteristics.
Methods
This national validation study was conducted across five epilepsy centers in the United States. Youth 5–18 years and caregivers of youth 2–18 years diagnosed with epilepsy completed the PedsQL Epilepsy...
The primary aim was to examine the preliminary efficacy of a family tailored problem‐solving intervention to improve antiepileptic drug (AED) adherence in families of children with new‐onset epilepsy. Secondary aims were to assess changes in targeted mechanisms and treatment feasibility and acceptability. Fifty families (Mage = 7.6 ± 3.0; 80% Caucasian; 42% idiopathic localization related) completed...
Purpose: Study aims were (1) to document and examine associations between parent‐report and electronic monitoring (EM) of pediatric antiepileptic drug (AED) adherence, (2) to determine the sensitivity and specificity of parent‐reported adherence, and (3) to develop a correction factor for parent‐reported adherence.
Methods: Participants included 111 consecutive children with new‐onset epilepsy (M...
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