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We present a 16-channel seizure detection system-on-chip (SoC) with 0.92µW/channel power dissipation in a total area of 1.1mm2 including a closed-loop neural stimulator. A set of four features are extracted from the spatially filtered neural data to achieve a high detection accuracy at minimal hardware cost. The performance is demonstrated by early detection and termination of kainic acid-induced...
Epilepsy is one of the most serious neurological diseases, affecting 1% of the world population. The disease is characterized by recurrent and spontaneous seizures due to the abnormal excessive activity of the neurons in the brain. The transition from a normal brain to a brain generating seizures, a process called epileptogenesis, is still unclear. For this reason, we explored the dynamics of the...
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