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Objective
Hypertension‐associated PA dysfunction reduces cerebral perfusion and impairs cognition. This is associated with impaired TRPV4‐mediated PA dilation; therefore, we tested the hypothesis that TRPV4 channels are important regulators of cerebral perfusion, PA structure and dilation, and cognition.
Methods
Ten‐ to twelve‐month‐old male TRPV4 knockout (WKY‐Trpv4em4Mcwi) and age‐matched control...
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