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MicroRNAs (miRNAs) are involved in the post‐transcriptional regulation of mRNAs. However, the function of miRNAs is unclear in epithelial–mesenchymal transition (EMT) of pterygium, a disease characterized by abnormal fibrovascular proliferation and invasion on the ocular surface. Since MiR‐3175 is upregulated in pterygium tissues compared to normal conjunctival tissues, in this study, we investigated...
β‐1,6‐N‐acetylglucosaminyltransferase 2 (GCNT2), which encodes a key glycosyltransferase for blood group I antigen synthesis, is induced upon epithelial–mesenchymal transition (EMT). Our results indicate that GCNT2 is upregulated upon EMT induced with epidermal growth factor and basic FGF in cultured human colon cancer cells. GCNT2 knockdown or overexpression decreases or increases, respectively,...
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