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In recent years, analytical glycomics gained a significant role due to the rapidly increasing number of glycoproteins introduced as biopharmaceuticals. One of the frequently used methods for the analysis of complex carbohydrates is capillary electrophoresis with laser induced fluorescent detection (CE-LIF). CE-LIF is a high resolution separation technique with excellent sensitivity capable of discriminating...
Recent emergence in the use of monoclonal antibody therapeutics and other glycoprotein biopharmaceuticals requires high‐throughput, robust, and automated techniques for their glycosylation analysis. Capillary electrophoresis is one of the high‐performance methods of choice; however, while the necessary instrumentation is well developed, the related bioinformatics tools are lacked behind. In this paper,...
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