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BackgroundWe evaluated the effects of a levosimendan (LS)‐based strategy compared with standard inotropic therapy on renal function in heart transplantation.
Methods and resultsUsing a randomized study design, 94 patients were assigned to LS‐based therapy or standard inotropic support. At the time of transplantation, the groups did not differ in age, gender, heart failure etiology, hemodynamic profile,...
Long-term impact of levosimendan on renal function remains undefined. Prospectively, we evaluated effects of levosimendan on renal function in patients with advanced chronic heart failure awaiting cardiac transplantation.Of 40 patients, 20 were randomized to receive levosimendan (10-minute bolus 12 μg/kg, followed by 0.1 μg/kg/min for 24 hours; LS Group), and 20 received no levosimendan (Controls)...
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