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Background and Aims
Although the Netherlands, Canada and Australia were early adopters of harm reduction for people who inject drugs (PWID), their respective HIV and hepatitis C (HCV) epidemics differ. We measured the pooled effect of needle and syringe program (NSP) and opioid agonist therapy (OAT) participation on HIV and HCV incidence in these settings.
Design
For each cohort, we emulated the...
Background and Aims
Income assistance is critical to the health and wellbeing of socio‐economically marginalized people who use illicit drugs (PWUD). However, past literature paradoxically identifies unintended increases in drug‐related harm coinciding with synchronized payments that may magnify signals for drug use. The scope of such harm has not been fully characterized among non‐institutionalized...
Background and aims
Injection drug use patterns are known to change over time, although such long‐term changes have not been well described. We sought to characterize longitudinal trajectories of injection drug use and identify associated factors.
Design
Data were derived from the Vancouver Injection Drug Users Study and AIDS Care Cohort to evaluate the Exposure to Survival Services study, two...
AimsTo estimate the relationship between daily alcohol use and HIV seroconversion among people who inject drugs (PWID) in a Canadian setting.
Design and SettingData from an open prospective cohort study of PWID in Vancouver, Canada, recruited via snowball sampling and street outreach between May 1996 and November 2013. An interviewer‐administered questionnaire including standardized behavioural assessment...
Background and AimsFor HIV‐positive individuals who use illicit opioids, engagement in methadone maintenance therapy (MMT) can contribute to improved HIV treatment outcomes. However, to our knowledge, the role of methadone dosing in adherence to antiretroviral therapy (ART) has not yet been investigated. We sought to examine the relationship between methadone dose and ART adherence among a cohort...
Aims
To determine the impact of HIV infection on mortality over time among people who inject drugs (PWID) in settings with free HIV/AIDS care.
Design and Setting
Prospective cohort study of PWID in Vancouver, Canada, recruited between May 1996 and December 2011. We ascertained morality rates and causes of death through a confidential linkage with the provincial vital statistics registry.
Participants...
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