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Background Many equations have been developed to estimate various body fluid volumes from height and weight, but few have been developed for children. The aim of this study was to compare four height/weight formulae for estimating extracellular fluid volume (eECV) in children against measured extracellular fluid volume (mECV). Methods The mECV was obtained from plasma Cr-51-EDTA clearance data used...
This study pools published data to describe the increase in glomerular filtration rate (GFR) from very premature neonates to young adults. The data comprises measured GFR (using polyfructose, 51Cr-EDTA, mannitol or iohexol) from eight studies (n = 923) and involved very premature neonates (22 weeks postmenstrual age) to adulthood (31 years). A nonlinear mixed effects approach (NONMEM) was used to...
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