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Paediatric patients with acute myeloid leukaemia (AML) who fail induction due to primary resistance to chemotherapy account for a significant proportion of cases and have a particularly dismal prognosis. We report the clinical and biological data, and final outcome of 48 paediatric patients with primary‐resistant AML enrolled in the Associazione Italiana di Ematologia e Oncologia Pediatrica AML 2002/01...
We report on the successful infusion of human adenovirus (HAdV)‐specific T cells in a child with congenital amegakaryocytic thrombocytopenia, given T‐cell‐depleted hematopoietic stem cell transplantation (HSCT) from the HLA‐haploidentical mother during extracorporeal membrane oxygenation (ECMO) for severe HAdV‐related respiratory failure. Donor‐derived, interferon (IFN)‐γ‐secreting HAdV‐specific T...
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