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Diffuse spread through brain parenchyma and the presence of hypoxic foci rimmed by neoplastic cells are two cardinal features of glioblastoma, and low oxygen is thought to drive movement of malignant gliomas in the core of the lesions. Transcription factors associated with epithelial‐to‐mesenchymal transition (EMT) have been linked to this invasion, and we found that hypoxia increased in vitro invasion...
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