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BACKGROUNDThe role of consolidation radiotherapy was examined for patients with diffuse large B‐cell lymphoma who were treated at institutions of the National Comprehensive Cancer Network during the rituximab era.
METHODSFailure‐free survival (FFS) and overall survival (OS) were analyzed in terms of patient and treatment characteristics. Potential associations were investigated with univariate and...
BACKGROUNDHigh‐dose thiotepa, busulfan, and cyclophosphamide (TBC) with autologous stem cell transplantation (ASCT) has been used in patients with central nervous system (CNS) involvement by non‐Hodgkin lymphoma (NHL). Despite limited penetration into the CNS, rituximab is active in primary CNS NHL. Therefore, high‐dose rituximab was combined with TBC for ASCT in patients with CNS NHL.
METHODSA single‐arm...
BACKGROUNDStem cell transplant (SCT)‐related outcomes and prognostication for relapsed/refractory follicular lymphoma (FL) are not well‐defined in the post‐rituximab era.
METHODSThrough the National Comprehensive Cancer Network (NCCN) lymphoma outcomes study, 184 patients with relapsed/refractory FL who underwent autologous SCT (autoSCT) or allogenic SCT (alloSCT) following disease relapse after...
BACKGROUND:Bortezomib has preclinical and clinical in B‐cell lymphomas, both alone and in combination with other agents. A phase 1 evaluation was conducted of bortezomib with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R‐CHOP) in patients with untreated diffuse large B‐cell lymphoma (DLBCL) or mantle cell lymphoma (MCL).
METHODS:Twenty patients (16 with DLBCL and 4...
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