Search results for: Li Lan

Items from 1 to 20 out of 271 results

article

Ameliorative effects of zinc and vitamin E against phthalates‐induced reproductive toxicity in male rats

Ling‐Zi Xia, Li‐Lan Liu, Jun‐Zhe Yue, Zhen‐Yu Lu, more

Environmental Toxicology > 39 > 6 > 3330 - 3340

Objective Phthalates (PEs) could cause reproductive harm to males. A mixture of three widely used PEs (MPEs) was used to investigate the ameliorative effects of zinc (Zn) and vitamin E (VE) against male reproductive toxicity. Methods Fifty male SD rats were randomly divided into five groups (n = 10). Rats in MPEs group were orally treated with 160 mg/kg/d MPEs, while rats in MPEs combined Zn and/or...

article

Revisiting Aurora Kinase B: A promising therapeutic target for cancer therapy

Naga Rajiv Lakkaniga, Zhengyu Wang, Yao Xiao, Anupreet Kharbanda, more

Medicinal Research Reviews > 44 > 2 > 686 - 706

Cancer continues to be a major health concern globally, although the advent of targeted therapy has revolutionized treatment options. Aurora Kinase B is a serine‐threonine kinase that has been explored as an oncology therapeutic target for more than two decades. Aurora Kinase B inhibitors show promising biological results in in‐vitro and in‐vivo experiments. However, there are no inhibitors approved...

article

Quercetin inhibits testicular toxicity induced by the mixture of three commonly used phthalates in rats

Ling‐Zi Xia, Ming‐Zhe Jiang, Li‐Lan Liu, Yi Wu, more

Journal of the Science of Food and Agriculture > 103 > 3 > 1541 - 1549

BACKGROUND Phthalates (PEs), such as butyl benzyl phthalate, dibutyl phthalate and di(2‐ethylhexyl) phthalate, are one of the most widely used plasticizers, and humans are increasingly exposed to them. Phytochemical quercetin (Que) is a typical flavonoid with several biological effects, such as antioxidative and anti‐inflammatory. The present study was designed to explore the effect of Que on testicular...

article

Experimental study of the negative effects of raised bedroom temperature and reduced ventilation on the sleep quality of elderly subjects

Yan Yan, Haodong Zhang, Mengyuan Kang, Li Lan, more

Indoor Air > 32 > 11 > n/a - n/a

This study investigated the effects of air temperature and ventilation on the sleep quality of elderly subjects and elucidated the mechanisms involved. Sixteen subjects aged over 65 years old were exposed to four conditions in a 2 × 2 design: air temperatures of 27°C and 30°C (with a ceiling fan in operation at 30°C) and two ventilation conditions (with and without mechanical ventilation) in experimental...

article

The effect of inhaled air temperature on thermal comfort, perceived air quality, acute health symptoms and physiological responses at two ambient temperatures

Zhibin Wu, Nianping Li, Li Lan, Pawel Wargocki

Indoor Air > 32 > 8 > n/a - n/a

We explored the importance of inhaled air temperature on thermal comfort, perceived air quality, acute non‐clinical health symptoms, and physiological responses. Sixteen subjects stayed in a stainless‐steel chamber for 90 min. They experienced four conditions with two inhaled air temperatures of 22 and 30°C and two ambient temperatures of 22 and 30°C in a 2 × 2 design. They wore breathing masks covering...

article

Synthesis of a highly stable Pt/CeO₂/Al₂O₃ catalyst for gasoline engine emission control by adjusting Pt distribution

Li Lan, Junhuai Xiang, Long Huang, Xin Huang, more

The Canadian Journal of Chemical Engineering > 100 > 4 > 827 - 837

For a CeO₂/Al₂O₃‐supported Pt catalyst system, the distribution of Pt is of significant importance to its hydrothermal stability and catalytic performance. Generally speaking, impregnation of a Pt precursor on CeO₂/Al₂O₃ composite is a commonly applied approach to synthesize the catalyst. In this work, partially calcined CeO₂ on Al₂O₃ was used as the support to modify Pt distribution. The characterization...

article

Cognitive performance was reduced by higher air temperature even when thermal comfort was maintained over the 24–28°C range

Li Lan, Jieyu Tang, Pawel Wargocki, David P Wyon, more

Indoor Air > 32 > 1 > n/a - n/a

This study managed to create thermal comfort conditions at three temperatures (24°C‐T24, 26°C‐T26, and 28°C‐T28) by adjusting clothing and air velocity. Thirty‐six subjects (18 males and 18 females) were exposed to each of the three conditions for 4.5 h in a design balanced for order of presentation of conditions. During each exposure, they rated the physical environment, their comfort, the intensity...

article

Emission rate of carbon dioxide while sleeping

Xiaojun Fan, Mitsuharu Sakamoto, Huiqi Shao, Kazuki Kuga, more

Indoor Air > 31 > 6 > 2142 - 2157

Humans emit carbon dioxide (CO₂) as a product of their metabolism. Its concentration in buildings is used as a marker of ventilation rate (VR) and degree of mixing of supply air, and indoor air quality (IAQ). The CO₂ emission rate (CER) may be used to estimate the ventilation rate. Many studies have measured CERs from subjects who were awake but little data are available from sleeping subjects and...

article

Pilot study of the effects of ventilation and ventilation noise on sleep quality in the young and elderly

Li Lan, Yuxiang Sun, David P. Wyon, Pawel Wargocki

Indoor Air > 31 > 6 > 2226 - 2238

Three conditions were established to investigate the effects of ventilation and related ventilation noise on sleep quality: No mechanical ventilation/low noise (A); Mechanical ventilation /low noise (B); Mechanical ventilation/high noise (C). The interventions were achieved by idling a mechanical ventilation system or operating it in two different modes. Nine young people and nine older people were...

article

Study on the mechanism of active components of Liupao tea on 3CL^pro based on HPLC‐DAD fingerprint and molecular docking technique

Wei‐Ju Ni, Xiao‐Xue Chen, Shu‐Yun Wei, Lun‐Li Lan, more

Journal of Food Biochemistry > 45 > 5 > n/a - n/a

Liupao tea, a drink homologous to medicine and food. It can treat dysentery, relieve heat, remove dampness, and regulate the intestines and stomach. The objective of this study is to explore the material basis and mechanism of Liupao tea intervention in COVID‐19 and to provide a new prevention and treatment programme for COVID‐19. We used high performance liquid chromatography to analyze the extract...

article

Health‐related quality of life of patients with colorectal neoplasms in China: A multicenter cross‐sectional survey

Hui‐Yao Huang, Hong Wang, Ju‐Fang Shi, Ya‐Na Bai, more

Journal of Gastroenterology and Hepatology > 36 > 5 > 1197 - 1207

Background and Aim This study aimed to clarify health‐related quality of life (HRQoL) of patients with colorectal precancer and colorectal cancer (CRC) in China and to better understand related utility scores. Methods A hospital‐based cross‐sectional survey was conducted in precancer and CRC patients from 2012 to 2014, covering 12 provinces in China. HRQoL was assessed with EuroQol 5‐Dimensions...

article

Short focal length tunable liquid crystal lenticular lens array based on fringe field effect

Rui Li, Fan Chu, Li‐Lan Tian, Xiao‐Qing Gu, more

Journal of the Society for Information Display > 28 > 10 > 793 - 800

A liquid crystal (LC) lenticular lens array based on fringe field effect is proposed. The gradient refractive index (GRIN) profile can be generated in the LC layer because of the fringe field between the strip‐shaped electrodes and the bottom electrode. The proposed LC lenticular lens array possesses ideal lens‐like phase profile and shortest focal length (1.199 mm) when the driving voltage is 5.4...

article

P‐139: Double‐side In‐plane‐switching Electrode Blue‐phase Liquid Crystal Display with Permittivity Protrusion

Li-Lan Tian, Fan Chu, Rui Li, Xiao-Qing Gu, more

SID Symposium Digest of Technical Papers > 51 > 1 > 1901 - 1903

We propose a transmissive double‐side in‐plane‐switching (IPS) electrodes blue‐phase liquid crystal display (LCD) with permittivity protrusion. The potential drops very slowly in the permittivity protrusions, thus the field penetrating depth is significantly enlarged and the operating voltage is lowered. This device has the advantages of fast response time, easy manufacturing process, and low operation...

article

Factors influencing the self‐perceived competencies in spiritual care of nurses in the long‐term care facilities

Mei‐Li Chen, Yi‐Heng Chen, Li‐Chan Lin, Li‐Lan Chuang

Journal of Nursing Management > 28 > 6 > 1286 - 1294

Aims To identify key factors influencing institutional nurses' self‐perceived competencies in spiritual care. Background In the past decade, interest in spiritual care has been increasing; however, in long‐term care facilities, limited knowledge is available about nurses' competencies in spiritual care. Methods The cross‐sectional study was conducted with 202 nurses in 11 long‐term care facilities...

article

A single‐cell‐gap transflective blue‐phase liquid crystal display based on fringe in‐plane switching electrodes

Xiang‐Yu Zhou, Fan Chu, Li‐Lan Tian, Rui Li, more

Journal of the Society for Information Display > 28 > 9 > 759 - 766

A transflective blue‐phase liquid crystal display (TRBP‐LCD) based on fringe in‐plane switching (FIS) electrodes is proposed. The proposed structure generates combined fringe and in‐plane electric fields that cause more liquid crystal (LC) molecules to reorient almost in plane above and between the pixel electrodes. The fringe field is mainly generated in the transmissive (T) region, and the horizontal...

article

Perceived air quality and cognitive performance decrease at moderately raised indoor temperatures even when clothed for comfort

Li Lan, Lulu Xia, Rihab Hejjo, David P. Wyon, more

Indoor Air > 30 > 5 > 841 - 859

This study investigated whether adjusting clothing to remain in neutral thermal comfort at moderately elevated temperature is capable of avoiding negative effects on perceived acute subclinical health symptoms, comfort, and cognitive performance. Two temperatures were examined: 23°C and 27°C. Twelve subjects were able to remain thermally comfortable at both temperatures by adjusting their clothing...

article

Resolution of ROS‐induced G‐quadruplexes and R‐loops at transcriptionally active sites is dependent on BLM helicase

Jun Tan, Xiangyu Wang, Laiyee Phoon, Haibo Yang, more

FEBS Letters > 594 > 9 > 1359 - 1367

R‐loops and G‐quadruplexes (G4s) are noncanonical secondary DNA structures. Here, we show that reactive oxygen species (ROS) induce G4 formation as well as R‐loops at transcriptionally active sites. Importantly, the G4 structure is subsequently triggered by R‐loop formation after damage. Once G4 is formed within an R‐loop, it reversely stabilizes the R‐loop. Notably, the helicase activity of Bloom...

article

Simulation study of single‐cell‐gap transflective liquid crystal display with nonuniform potential

Fan Chu, Li‐Lan Tian, Hu Dou, Rui Li, more

Journal of the Society for Information Display > 28 > 2 > 148 - 156

A single‐cell‐gap transflective liquid crystal display with a nonuniform electric potential is demonstrated. The top substrate has a top planar common electrode, a transparent dielectric layer with a general dielectric constant is coated on the bottom substrate, and two planar pixel electrodes with the same size are coated on the dielectric layer and the bottom substrate, respectively. With the different...

article

Influence of cancellous bone microstructure on ultrasonic attenuation: a theoretical prediction

Jinjin Liu, Li Lan, Jiafeng Zhou, Yunjun Yang

BioMedical Engineering OnLine > 2019 > 18 > 1 > 1-10

Background Quantitative ultrasound has been used for the assessment of cancellous bone status. The attenuation mechanisms of cancellous bone, however, have not been well understood, because the microstructure of cancellous bone is significantly inhomogeneous and the interaction between ultrasound and the microstructure of cancellous bone is complex. In this study, a theoretical approach was applied...

article

Elevated airflow can maintain sleep quality and thermal comfort of the elderly in a hot environment

Li Lan, Lulu Xia, Jieyu Tang, Xiaojing Zhang, more

Indoor Air > 29 > 6 > 1040 - 1049

The effect of elevated airflow on sleep quality was investigated with 18 elderly. Three airflow conditions were set: ceiling fan/30°C/max.0.8 m/s and mean 0.7 m/s, task fan/30°C/max.0.8 m/s and mean 0.6 m/s, and thermally neutral /27°C/0.2 m/s. Sleep quality was evaluated objectively by analysis of electroencephalogram signals that were continuously monitored during the sleeping period. Urinary cortisol...

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INFONA - science communication portal

Search results for: Li Lan

Ameliorative effects of zinc and vitamin E against phthalates‐induced reproductive toxicity in male rats

Revisiting Aurora Kinase B: A promising therapeutic target for cancer therapy

Quercetin inhibits testicular toxicity induced by the mixture of three commonly used phthalates in rats

Experimental study of the negative effects of raised bedroom temperature and reduced ventilation on the sleep quality of elderly subjects

The effect of inhaled air temperature on thermal comfort, perceived air quality, acute health symptoms and physiological responses at two ambient temperatures

Synthesis of a highly stable Pt/CeO₂/Al₂O₃ catalyst for gasoline engine emission control by adjusting Pt distribution

Cognitive performance was reduced by higher air temperature even when thermal comfort was maintained over the 24–28°C range

Emission rate of carbon dioxide while sleeping

Pilot study of the effects of ventilation and ventilation noise on sleep quality in the young and elderly

Study on the mechanism of active components of Liupao tea on 3CL^pro based on HPLC‐DAD fingerprint and molecular docking technique

Health‐related quality of life of patients with colorectal neoplasms in China: A multicenter cross‐sectional survey

Short focal length tunable liquid crystal lenticular lens array based on fringe field effect

P‐139: Double‐side In‐plane‐switching Electrode Blue‐phase Liquid Crystal Display with Permittivity Protrusion

Factors influencing the self‐perceived competencies in spiritual care of nurses in the long‐term care facilities

A single‐cell‐gap transflective blue‐phase liquid crystal display based on fringe in‐plane switching electrodes

Perceived air quality and cognitive performance decrease at moderately raised indoor temperatures even when clothed for comfort

Resolution of ROS‐induced G‐quadruplexes and R‐loops at transcriptionally active sites is dependent on BLM helicase

Simulation study of single‐cell‐gap transflective liquid crystal display with nonuniform potential

Influence of cancellous bone microstructure on ultrasonic attenuation: a theoretical prediction

Elevated airflow can maintain sleep quality and thermal comfort of the elderly in a hot environment

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