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This paper reports the multiplexed monitoring of two promising biomarkers, beta-amyloid (Aβ42) and total tau (T-tau), in both buffer and cerebrospinal fluid (CSF) for Alzheimer's disease (AD) using label-free optical nanosensors. It has been found that 7.8 pg/ml of Aβ42 in buffer and 15.6 pg/ml of T-au in buffer can be readily detected with very good specificity. Based on our measurements, the purchased...
This paper reports for the first time the monitoring of two types of promising biomarkers, beta-amyloid (Aβ42) and total tau (T-tau), in both buffer and cerebrospinal fluid from pooled Human donors for Alzheimer's disease (AD) using label-free optical nanosensors. Experiments found that as low as ∼15.6 pg/ml of Aβ42 in buffer can be readily detected by the sensor with very good specificity. Aβ42 spiked...
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