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Tumour‐derived CXCL8 facilitates the movement of myeloid‐derived suppressor cells, which are able to restrain antitumour immune responses to the tumour microenvironment. Kruppel‐like factor 4 (KLF4) is a potential tumour suppressor in gastric cancer (GC). However, knowledge regarding correlations between KLF4 and CXCL8 in GC is limited. We use cellular and molecular biological methods to assess whether...