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Premature ovarian insufficiency (POI) is defined as a primary ovarian defect characterized by absent menarche (primary amenorrhea) or premature depletion of ovarian follicles before the age of 40 (secondary amenorrhea) with hypergonadotropism and hypoestrogenism.We studied the clinical, biological, and genetic data related to 50 POI patients with a mean age of menopause of 29years (94% with secondary...
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