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A multicenter, 12-week, double-blind, flexible dose study of outpatients with a DSM-III-R diagnosis of posttraumatic stress disorder (PTSD) was conducted at 12 US centers to evaluate the safety and efficacy of sertraline compared to placebo. Two hundred and eight patients 18 years of age and older received double-blind treatment with either sertraline (n = 100) or placebo (n = 108). After a one-week...
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