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Background
It is questionable whether enrollment on clinical trials offers any survival advantage at the population level over standard‐of‐care treatment. The objectives of this study were to describe the impact of trial enrollment on event‐free survival and overall survival in pediatric acute myeloid leukemia (AML) using the Cancer in Young People in Canada (CYP‐C) database.
Methods
Children were...
Background Primary objective was to describe the proportion of children newly diagnosed with cancer enrolled on a therapeutic clinical trial. Secondary objectives were to describe reasons for non-enrollment and factors associated with enrollment on trials. Methods In this retrospective cohort study, we included children newly diagnosed with cancer between 0 and 14 years of age and diagnosed from...
BACKGROUNDPediatric cancer distribution and outcomes have not been examined in Canadian Aboriginal children. The objective of this study was to describe the distribution, event‐free survival, and overall survival of Aboriginal children with malignancies who reside in Ontario compared with non‐Aboriginal children.
METHODSThis population‐based study included 10,520 Ontario children (aged <18 years)...
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