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ObjectiveInterferon regulatory factor 5 (IRF‐5) is a transcription factor that mediates intracellular signals activated by engagement of Toll‐like receptors (TLRs). IRF5 polymorphisms are associated with an increased or decreased risk of systemic lupus erythematosus (SLE) in various human populations, but the precise role of IRF5 in SLE development is not fully understood. This study was undertaken...
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